Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus
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چکیده
منابع مشابه
wuthering heights and the concept of marality/a sociological study of the novel
to discuss my point, i have collected quite a number of articles, anthologies, and books about "wuthering heights" applying various ideas and theories to this fantastic story. hence, i have come to believe that gadamer and jauss are rightful when they claim that "the individaul human mind is the center and origin of all meaning," 3 that reading literature is a reader-oriented activity, that it ...
15 صفحه اولanalysis of natural compounds targeting structural and In silico nonstructural proteins of chikungunya virus
Chikungunya fever presents as a high-grade fever during its Background: acute febrile phase and can be prolonged for months as chronic arthritis in affected individuals. Currently, there are no effective drugs or vaccines against this virus. The present study was undertaken to evaluate protein-ligand interactions of all chikungunya virus (CHIKV) proteins with natural compounds from a MolBase li...
متن کاملAntiviral Perspectives for Chikungunya Virus
Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has a major health impact in humans and causes acute febrile illness in humans accompanied by joint pains and, in many cases, persistent arthralgia lasting for weeks to years. CHIKV reemerged in 2005-2006 in several parts of the Indian Ocean islands and India after a gap of 32 years, causing millions of cases. The re-emergence of CHIKV...
متن کاملIn silico analysis of natural compounds targeting structural and nonstructural proteins of chikungunya virus
Background: Chikungunya fever presents as a high-grade fever during its acute febrile phase and can be prolonged for months as chronic arthritis in affected individuals. Currently, there are no effective drugs or vaccines against this virus. The present study was undertaken to evaluate protein-ligand interactions of all chikungunya virus (CHIKV) proteins with natural compounds from a MolBase li...
متن کاملRotavirus Nonstructural Protein 4 (NSP4)-Viral Enterotoxin with Multiple roles in Pathogenesis of Diarrhoea in Children
Article history: Received on: 06/05/2015 Revised on: 24/05/2015 Accepted on: 14/07/2015 Available online: 27/07/2015 Nonstructural protein 4 (NSP4) of Rotavirus has been designated as the first viral enterotoxin. Its role in viral replication is already well known. Intensive research over the past decade has shown the involvement of this protein in many cellular activities both in ‘expressed’ a...
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ژورنال
عنوان ژورنال: Virology
سال: 2017
ISSN: 0042-6822
DOI: 10.1016/j.virol.2017.02.014